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Engineered antibody fragments for immuno-PET imaging of endogenous CD8(+) T cells in vivo

The noninvasive detection and quantification of CD8(+) T cells in vivo are important for both the detection and staging of CD8(+) lymphomas and for the monitoring of successful cancer immunotherapies, such as adoptive cell transfer and antibody-based immunotherapeutics. Here, antibody fragments are...

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Autors principals: Tavaré, Richard, McCracken, Melissa N., Zettlitz, Kirstin A., Knowles, Scott M., Salazar, Felix B., Olafsen, Tove, Witte, Owen N., Wu, Anna M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903195/
https://ncbi.nlm.nih.gov/pubmed/24390540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316922111
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