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Steroidogenic activity of a peptide specified by the reversed sequence of corticotropin mRNA.

The molecular recognition theory predicts that a reversed (3'----5') reading of an mRNA should yield a peptide that is structurally and functionally similar to that specified in the 5'----3' direction. We tested this idea by synthesizing a corticotropin (ACTH) analogue using a reverse reading of bov...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Clarke, B L, Blalock, J E
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1990
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55242/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2175911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9708
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