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Steroidogenic activity of a peptide specified by the reversed sequence of corticotropin mRNA.

The molecular recognition theory predicts that a reversed (3'----5') reading of an mRNA should yield a peptide that is structurally and functionally similar to that specified in the 5'----3' direction. We tested this idea by synthesizing a corticotropin (ACTH) analogue using a re...

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Autors principals: Clarke, B L, Blalock, J E
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55242/
https://ncbi.nlm.nih.gov/pubmed/2175911
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