Steroidogenic activity of a peptide specified by the reversed sequence of corticotropin mRNA.
The molecular recognition theory predicts that a reversed (3'----5') reading of an mRNA should yield a peptide that is structurally and functionally similar to that specified in the 5'----3' direction. We tested this idea by synthesizing a corticotropin (ACTH) analogue using a reverse reading of bov...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2175911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9708 |
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