Alogliptin, a Dipeptidyl Peptidase‐4 Inhibitor, Alleviates Atrial Remodeling and Improves Mitochondrial Function and Biogenesis in Diabetic Rabbits

BACKGROUND: There is increasing evidence implicating atrial mitochondrial dysfunction in the pathogenesis of atrial fibrillation. In this study, we explored whether alogliptin, a dipeptidyl peptidase‐4 inhibitor, can prevent mitochondrial dysfunction and atrial remodeling in a diabetic rabbit model....

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Zhang, Xiaowei, Zhang, Zhiwei, Zhao, Yungang, Jiang, Ning, Qiu, Jiuchun, Yang, Yajuan, Li, Jian, Liang, Xue, Wang, Xinghua, Tse, Gary, Li, Guangping, Liu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524117/
https://ncbi.nlm.nih.gov/pubmed/28507060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.005945
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