Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

BACKGROUND: The amino acid response (AAR) is an evolutionarily conserved protective mechanism activated by amino acid deficiency through a key kinase, general control nonderepressible 2. In addition to mobilizing amino acids, the AAR broadly affects gene and protein expression in a variety of pathwa...

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Bibliografiska uppgifter
I publikationen:J Am Heart Assoc
Huvudupphovsmän: Qin, Pu, Arabacilar, Pelin, Bernard, Roberta E., Bao, Weike, Olzinski, Alan R., Guo, Yuanjun, Lal, Hind, Eisennagel, Stephen H., Platchek, Michael C., Xie, Wensheng, del Rosario, Julius, Nayal, Mohamad, Lu, Quinn, Roethke, Theresa, Schnackenberg, Christine G., Wright, Fe, Quaile, Michael P., Halsey, Wendy S., Hughes, Ashley M., Sathe, Ganesh M., Livi, George P., Kirkpatrick, Robert B., Qu, Xiaoyan A., Rajpal, Deepak K., Faelth Savitski, Maria, Bantscheff, Marcus, Joberty, Gerard, Bergamini, Giovanna, Force, Thomas L., Gatto, Gregory J., Hu, Erding, Willette, Robert N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524058/
https://ncbi.nlm.nih.gov/pubmed/28487390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004453
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