Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

BACKGROUND: The amino acid response (AAR) is an evolutionarily conserved protective mechanism activated by amino acid deficiency through a key kinase, general control nonderepressible 2. In addition to mobilizing amino acids, the AAR broadly affects gene and protein expression in a variety of pathwa...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Qin, Pu, Arabacilar, Pelin, Bernard, Roberta E., Bao, Weike, Olzinski, Alan R., Guo, Yuanjun, Lal, Hind, Eisennagel, Stephen H., Platchek, Michael C., Xie, Wensheng, del Rosario, Julius, Nayal, Mohamad, Lu, Quinn, Roethke, Theresa, Schnackenberg, Christine G., Wright, Fe, Quaile, Michael P., Halsey, Wendy S., Hughes, Ashley M., Sathe, Ganesh M., Livi, George P., Kirkpatrick, Robert B., Qu, Xiaoyan A., Rajpal, Deepak K., Faelth Savitski, Maria, Bantscheff, Marcus, Joberty, Gerard, Bergamini, Giovanna, Force, Thomas L., Gatto, Gregory J., Hu, Erding, Willette, Robert N.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524058/
https://ncbi.nlm.nih.gov/pubmed/28487390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004453
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