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Design, synthesis and evaluation of antitumor acylated monoaminopyrroloquinazolines
Pyrroloquinazoline is a privileged chemical scaffold with diverse biological activities. We recently described a series of N-3 acylated 1,3-diaminopyrroloquinazolines with potent anticancer activities. The N-1 primary amino group in 1,3-diaminopyrroloquinazoline is critical for its inhibitory activi...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5523855/ https://ncbi.nlm.nih.gov/pubmed/28552339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.05.038 |
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