Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors

Evidence is mounting that the major histocompatibility complex (MHC) molecule HLA-F regulates the immune system in pregnancy, infection, and autoimmunity by signaling through NK-cell receptors (NKRs). We present structural, biochemical and evolutionary analyses demonstrating that HLA-F presents pept...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Dulberger, Charles L., McMurtrey, Curtis P., Hölzemer, Angelique, Neu, Karlynn E., Liu, Victor, Steinbach, Adriana M., Garcia-Beltran, Wilfredo F., Sulak, Michael, Jabri, Bana, Lynch, Vincent J., Altfeld, Marcus, Hildebrand, William H., Adams, Erin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523829/
https://ncbi.nlm.nih.gov/pubmed/28636952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.06.002
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