Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion

BACKGROUND: Cardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac hypertrophy, interstitial fibrosis, and myocyte apoptosis after permanent coronary ligation, findings that support S100A6 as a potential therapeu...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Mofid, Azadeh, Newman, Nadav S., Lee, Paul J. H., Abbasi, Cynthia, Matkar, Pratiek N., Rudenko, Dmitriy, Kuliszewski, Michael A., Chen, Hao H., Afrasiabi, Kolsoom, Tsoporis, James N., Gramolini, Anthony O., Connelly, Kim A., Parker, Thomas G., Leong‐Poi, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523770/
https://ncbi.nlm.nih.gov/pubmed/28174168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004738
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