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Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy

Ultrasound-targeted microbubble destruction (UTMD) can be used to deliver silencing gene therapy to tumors. We hypothesized that UTMD would be effective in suppressing angiogenesis within tumors, and that modulation of the ultrasound pulsing intervals (PI) during UTMD would affect the magnitude of t...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Fujii, Hiroko, Matkar, Pratiek, Liao, Christine, Rudenko, Dmitriy, Lee, Paul JH, Kuliszewski, Michael A, Prud'homme, Gerald J, Leong-Poi, Howard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817934/
https://ncbi.nlm.nih.gov/pubmed/23695537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.20
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