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Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy

Ultrasound-targeted microbubble destruction (UTMD) can be used to deliver silencing gene therapy to tumors. We hypothesized that UTMD would be effective in suppressing angiogenesis within tumors, and that modulation of the ultrasound pulsing intervals (PI) during UTMD would affect the magnitude of t...

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Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Fujii, Hiroko, Matkar, Pratiek, Liao, Christine, Rudenko, Dmitriy, Lee, Paul JH, Kuliszewski, Michael A, Prud'homme, Gerald J, Leong-Poi, Howard
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817934/
https://ncbi.nlm.nih.gov/pubmed/23695537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.20
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