Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy

Ultrasound-targeted microbubble destruction (UTMD) can be used to deliver silencing gene therapy to tumors. We hypothesized that UTMD would be effective in suppressing angiogenesis within tumors, and that modulation of the ultrasound pulsing intervals (PI) during UTMD would affect the magnitude of t...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Fujii, Hiroko, Matkar, Pratiek, Liao, Christine, Rudenko, Dmitriy, Lee, Paul JH, Kuliszewski, Michael A, Prud'homme, Gerald J, Leong-Poi, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817934/
https://ncbi.nlm.nih.gov/pubmed/23695537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.20
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