Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction

BACKGROUND: Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling. Organic nitrates reduce wave reflections acutely, but whether this is sustained chronically or affected by hydral...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Zamani, Payman, Akers, Scott, Soto‐Calderon, Haideliza, Beraun, Melissa, Koppula, Maheswara R., Varakantam, Swapna, Rawat, Deepa, Shiva‐Kumar, Prithvi, Haines, Philip G., Chittams, Jesse, Townsend, Raymond R., Witschey, Walter R., Segers, Patrick, Chirinos, Julio A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523746/
https://ncbi.nlm.nih.gov/pubmed/28219917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004262
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