Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction

BACKGROUND: Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling. Organic nitrates reduce wave reflections acutely, but whether this is sustained chronically or affected by hydral...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Zamani, Payman, Akers, Scott, Soto‐Calderon, Haideliza, Beraun, Melissa, Koppula, Maheswara R., Varakantam, Swapna, Rawat, Deepa, Shiva‐Kumar, Prithvi, Haines, Philip G., Chittams, Jesse, Townsend, Raymond R., Witschey, Walter R., Segers, Patrick, Chirinos, Julio A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523746/
https://ncbi.nlm.nih.gov/pubmed/28219917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004262
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