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Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway
OBJECTIVE: Curcumin (diferuloylmethane) is a yellow-colored polyphenol with antiproliferative and proapoptotic activities to various types of cancer cells. This study explored the mechanism by which curcumin induces p53-null hepatoma cell apoptosis. RESULTS: AKT, FOXO1, and FOXO3 proteins were downr...
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| Publicado no: | Evid Based Complement Alternat Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5523542/ https://ncbi.nlm.nih.gov/pubmed/28769986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4063865 |
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