Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors

Cancer is associated with alterations in epigenetic mechanisms such as histone modifications and methylation of DNA, and inhibitors targeting epigenetic mechanisms represent a novel class of anti-cancer drugs. Neuroendocrine tumors (NETs) of the pancreas (PNETs) and bronchus (BNETs), which may have...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Lines, K E, Stevenson, M, Filippakopoulos, P, Müller, S, Lockstone, H E, Wright, B, Grozinsky-Glasberg, S, Grossman, A B, Knapp, S, Buck, D, Bountra, C, Thakker, R V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523063/
https://ncbi.nlm.nih.gov/pubmed/28504695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.30
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