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A bispecific antibody targeting IGF-IR and EGFR has tumor and metastasis suppressive activity in an orthotopic xenograft osteosarcoma mouse model

Osteosarcoma is a highly aggressive bone cancer and the second most frequent cause of cancer-associated death in childhood and adolescence. Pulmonary metastases account for the high mortality rate in osteosarcoma patients. Therefore, novel therapeutic approaches, efficiently restraining the metastat...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Gvozdenovic, Ana, Boro, Aleksandar, Born, Walter, Muff, Roman, Fuchs, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523026/
https://ncbi.nlm.nih.gov/pubmed/28744395
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