Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice

More effective treatment of metastasizing osteosarcoma with a current mean 5-year survival rate of less than 20% requires more detailed knowledge on mechanisms and key regulatory molecules of the complex metastatic process. CXCR4, the receptor of the chemokine CXCL12, has been reported to promote tu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brennecke, Patrick, Arlt, Matthias J. E., Muff, Roman, Campanile, Carmen, Gvozdenovic, Ana, Husmann, Knut, Holzwarth, Nathalie, Cameroni, Elisabetta, Ehrensperger, Felix, Thelen, Marcus, Born, Walter, Fuchs, Bruno
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769403/
https://ncbi.nlm.nih.gov/pubmed/24040160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074045
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