Big conductance calcium‐activated potassium channel openers control spasticity without sedation

BACKGROUND AND PURPOSE: Our initial aim was to generate cannabinoid agents that control spasticity, occurring as a consequence of multiple sclerosis (MS), whilst avoiding the sedative side effects associated with cannabis. VSN16R was synthesized as an anandamide (endocannabinoid) analogue in an anti...

詳細記述

保存先:
書誌詳細
出版年:Br J Pharmacol
主要な著者: Baker, David, Pryce, Gareth, Visintin, Cristina, Sisay, Sofia, Bondarenko, Alexander I, Vanessa Ho, W S, Jackson, Samuel J, Williams, Thomas E, Al‐Izki, Sarah, Sevastou, Ioanna, Okuyama, Masahiro, Graier, Wolfgang F, Stevenson, Lesley A, Tanner, Carolyn, Ross, Ruth, Pertwee, Roger G, Henstridge, Christopher M, Irving, Andrew J, Schulman, Jesse, Powell, Keith, Baker, Mark D, Giovannoni, Gavin, Selwood, David L
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522996/
https://ncbi.nlm.nih.gov/pubmed/28677901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13889
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