Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB(2) Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis

Endocannabinoids and some phytocannabinoids bind to CB(1) and CB(2) cannabinoid receptors, transient receptor potential vanilloid one (TRPV1) receptor and the orphan G protein receptor fifty-five (GPR55). Studies using C57BL/10 and C57BL/6 (Cnr2 (tm1Zim)) CB(2) cannabinoid receptor knockout mice hav...

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Detalhes bibliográficos
Main Authors: Sisay, Sofia, Pryce, Gareth, Jackson, Samuel J., Tanner, Carolyn, Ross, Ruth A., Michael, Gregory J., Selwood, David L., Giovannoni, Gavin, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793915/
https://ncbi.nlm.nih.gov/pubmed/24130809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076907
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