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Mutation Spectrum of STAR and the Founder Effect of p.Q258* in Korean Patients with Congenital Lipoid Adrenal Hyperplasia

Congenital lipoid adrenal hyperplasia (CLAH) is the most severe form of congenital adrenal hyperplasia, caused by defects in the steroidogenic acute regulatory protein (STAR). The STAR p.Q258* mutation is the most common mutation in China, Japan and Korea, suggesting a founder effect. This study aim...

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Dades bibliogràfiques
Publicat a:Mol Med
Autors principals: Kang, Eungu, Kim, Yoon-Myung, Kim, Gu-Hwan, Lee, Beom Hee, Yoo, Han-Wook, Choi, Jin-Ho
Format: Artigo
Idioma:Inglês
Publicat: Feinstein Institute for Medical Research 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522967/
https://ncbi.nlm.nih.gov/pubmed/28467518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2017.00023
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