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Mutation Spectrum of STAR and the Founder Effect of p.Q258* in Korean Patients with Congenital Lipoid Adrenal Hyperplasia

Congenital lipoid adrenal hyperplasia (CLAH) is the most severe form of congenital adrenal hyperplasia, caused by defects in the steroidogenic acute regulatory protein (STAR). The STAR p.Q258* mutation is the most common mutation in China, Japan and Korea, suggesting a founder effect. This study aim...

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Bibliografski detalji
Izdano u:Mol Med
Glavni autori: Kang, Eungu, Kim, Yoon-Myung, Kim, Gu-Hwan, Lee, Beom Hee, Yoo, Han-Wook, Choi, Jin-Ho
Format: Artigo
Jezik:Inglês
Izdano: Feinstein Institute for Medical Research 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522967/
https://ncbi.nlm.nih.gov/pubmed/28467518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2017.00023
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