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Loss of Huntingtin stimulates capture of retrograde dense-core vesicles to increase synaptic neuropeptide stores
The Huntington’s disease protein Huntingtin (Htt) regulates axonal transport of dense-core vesicles (DCVs) containing neurotrophins and neuropeptides. DCVs travel down axons to reach nerve terminals where they are either captured in synaptic boutons to support later release or reverse direction to r...
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| Publicado no: | Eur J Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522648/ https://ncbi.nlm.nih.gov/pubmed/28129919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2017.01.001 |
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