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Vesicle capture, not delivery, scales up neuropeptide storage in neuroendocrine terminals

Neurons vary in their capacity to produce, store, and release neuropeptides packaged in dense-core vesicles (DCVs). Specifically, neurons used for cotransmission have terminals that contain few DCVs and many small synaptic vesicles, whereas neuroendocrine neuron terminals contain many DCVs. Although...

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Bibliographic Details
Main Authors: Bulgari, Dinara, Zhou, Chaoming, Hewes, Randall S., Deitcher, David L., Levitan, Edwin S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948302/
https://ncbi.nlm.nih.gov/pubmed/24550480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322170111
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