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The amino-terminal structures that determine topological orientation of cytochrome P-450 in microsomal membrane.

We previously showed that the amino-terminal region of P-450 is responsible not only for targeting to endoplasmic reticulum (ER) membrane but also for stable anchoring to the membrane. In the present study, we introduced several mutations or deletions into the signal-anchor region of the chimeric pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Sato, T, Sakaguchi, M, Mihara, K, Omura, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552263/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2369895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07414.x
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