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Significance of the third tRNA binding site, the E site, on E. coli ribosomes for the accuracy of translation: an occupied E site prevents the binding of non-cognate aminoacyl-tRNA to the A site.

The E site (exit site for deacyl-tRNA) has been shown to be allosterically linked to the A site (aminoacyl-tRNA binding site), in that occupation of the E site reduces the affinity of the A site, and vice versa, whereas the intervening peptidyl-tRNA binding site (P site) keeps its high affinity. Her...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Geigenmüller, U, Nierhaus, K H
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552248/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2265616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07904.x
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