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Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models
Heat shock protein 90 is a molecular chaperon that maintains the correct folding and function of multiple client proteins. The inhibition of heat shock protein 90, which leads to the simultaneous degradation of multiple proteins involved in oncogenic signaling pathways, has revealed an innovative st...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522292/ https://ncbi.nlm.nih.gov/pubmed/28476040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17180 |
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