IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65

The diffusely infiltrative nature of glioblastoma (GBM) makes them highly recurrent. IGF2 mRNA-binding protein 3 (IMP3), a GBM upregulated RNA binding protein, promotes glioma cell migration. An integrative bioinformatics analysis identified p65 (RELA), a subunit of NF-κB heterodimer as a target and...

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Udgivet i:Oncotarget
Main Authors: Bhargava, Shruti, Visvanathan, Abhirami, Patil, Vikas, Kumar, Anuj, Kesari, Santosh, Das, Saumitra, Hegde, Alangar S, Arivazhagan, Arimappamagan, Santosh, Vani, Somasundaram, Kumaravel
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522290/
https://ncbi.nlm.nih.gov/pubmed/28465487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17118
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