Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription

Glioblastomas (GBM) are the most malignant form of astrocytomas which are difficult to treat and portend a grave clinical course and poor prognosis. In this study, we identified Chromobox homolog 7 (Cbx7), a member of Polycomb Repressive Complex 1 (PRC1), as a downregulated gene in GBM owing to its...

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Publicado en:Sci Rep
Autores principales: Nawaz, Zahid, Patil, Vikas, Arora, Anjali, Hegde, Alangar S., Arivazhagan, Arimappamagan, Santosh, Vani, Somasundaram, Kumaravel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904208/
https://ncbi.nlm.nih.gov/pubmed/27291091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27753
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