SET mediates TCE-induced liver cell apoptosis through dephosphorylation and upregulation of nucleolin

Trichloroethylene (TCE) is an occupational and environmental chemical that can cause severe hepatotoxicity. While our previous studies showed that the phosphatase inhibitor SET is a key mediator of TCE-induced liver cell apoptosis, the molecular mechanisms remain elusive. Using quantitative phosphop...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ren, Xiaohu, Huang, Xinfeng, Yang, Xifei, Liu, Yungang, Liu, Wei, Huang, Haiyan, Wu, Desheng, Zou, Fei, Liu, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522280/
https://ncbi.nlm.nih.gov/pubmed/28402964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16785
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