Detection of oncogenic mutations in resected bronchial margins by next-generation sequencing indicates early relapse in stage IA lung adenocarcinoma patients

Stage I non-small cell lung cancer (NSCLC) patients experience a relatively high rate of recurrence, ranging from about 30-35%. We hypothesized that this elevated risk of recurrence is due to the presence of tumor cells at bronchial margins which was undetected by conventional light microscopy. Pati...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lv, Tangfeng, Zou, Jiawei, Liu, Hongbing, Shen, Qin, Lu, Zhenfeng, Zhou, XiaoJun, Wang, Xiaonan, Song, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522272/
https://ncbi.nlm.nih.gov/pubmed/28380452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16539
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