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Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway

Although initially effective against metastatic colorectal cancer (CRC), irinotecan-based chemotherapy leads to resistance and adverse toxicity. Curcumin is well known for its anti-cancer effects in many cancers, including CRC. Here, we describe reactive oxygen species (ROS) generation and endoplasm...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Huang, Yan-Feng, Zhu, Da-Jian, Chen, Xiao-Wu, Chen, Qi-Kang, Luo, Zhen-Tao, Liu, Chang-Chun, Wang, Guo-Xin, Zhang, Wei-Jie, Liao, Nv-Zhu
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522238/
https://ncbi.nlm.nih.gov/pubmed/28402965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16828
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