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Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors

More than 40 years ago, we discovered that novel transplantation antigens can be induced in vivo or in vitro by treating murine leukemia with dacarbazine. Years later, this phenomenon that we called “Chemical Xenogenization” (CX) and more recently, “Drug-Induced Xenogenization” (DIX), was reproduced...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Franzese, Ornella, Torino, Francesco, Fuggetta, Maria Pia, Aquino, Angelo, Roselli, Mario, Bonmassar, Enzo, Giuliani, Anna, D’Atri, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522228/
https://ncbi.nlm.nih.gov/pubmed/28404974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16335
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