Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors

More than 40 years ago, we discovered that novel transplantation antigens can be induced in vivo or in vitro by treating murine leukemia with dacarbazine. Years later, this phenomenon that we called “Chemical Xenogenization” (CX) and more recently, “Drug-Induced Xenogenization” (DIX), was reproduced...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Franzese, Ornella, Torino, Francesco, Fuggetta, Maria Pia, Aquino, Angelo, Roselli, Mario, Bonmassar, Enzo, Giuliani, Anna, D’Atri, Stefania
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522228/
https://ncbi.nlm.nih.gov/pubmed/28404974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16335
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