The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro

BACKGROUND: Saquinavir, a protease inhibitor utilized in HIV infection, shows antitumor activity in various experimental models. In previous studies performed in our laboratory the drug was found to induce a substantial increase of telomerase activity in normal peripheral blood mononuclear cells. Ai...

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Detalhes bibliográficos
Main Authors: Adamo, Riccardo, Comandini, Alessandro, Aquino, Angelo, Bonmassar, Laura, Guglielmi, Loredana, Bonmassar, Enzo, Franzese, Ornella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682913/
https://ncbi.nlm.nih.gov/pubmed/23759068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-38
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