A Longitudinal Biomarker for the Extent of Skin Disease in Patients with Diffuse Cutaneous Systemic Sclerosis

OBJECTIVE: The goal of this study was to define a pharmacodynamic biomarker based on gene expression in skin that would provide a biological measure of disease extent in patients with diffuse cutaneous systemic sclerosis (dcSSc) and that could be used to monitor skin disease longitudinally. METHODS:...

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Pubblicato in:Arthritis Rheumatol
Autori principali: Rice, Lisa M., Ziemek, Jessica, Stratton, Eric A., McLaughlin, Sarah R., Padilla, Cristina M., Mathes, Allison L., Christmann, Romy B., Stifano, Giuseppina, Browning, Jeffrey L., Whitfield, Michael L., Spiera, Robert F., Gordon, Jessica K., Simms, Robert W., Zhang, Yuqing, Lafyatis, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522178/
https://ncbi.nlm.nih.gov/pubmed/26240058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39287
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