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Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: involvement of mannosyl-phosphoryldolichol as the mannose donor.

Trypanosome variant surface glycoproteins (VSGs) exemplify a class of eukaryotic cell-surface glycoproteins that rely on a covalently attached lipid, glycosyl-phosphatidylinositol, for membrane attachment. The glycolipid anchor is acquired soon after translation of the polypeptide, apparently by rep...

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Bibliographic Details
Main Authors: Menon, A K, Mayor, S, Schwarz, R T
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC552207/
https://ncbi.nlm.nih.gov/pubmed/2148289
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