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Cytosine Iminyl Radical (cytN•) Formation via Electron Induced Debromination of 5-Bromocytosine: A DFT and Gaussian 4 study
Halogen-substituted pyrimidines, such as 5-bromouracil and 5-iodouracil, have been used as radio therapeutic (RT) agents in cancer treatment. The radiosensitizer activity of 5-bromouracil is attributed to its reaction with electron which produce the highly reactive uracil-5-yl radical by dissociatin...
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| Publié dans: | J Phys Chem A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521985/ https://ncbi.nlm.nih.gov/pubmed/28586202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpca.7b04034 |
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