Melatonin pre-treatment mitigates SHSY-5Y cells against oxaliplatin induced mitochondrial stress and apoptotic cell death

Oxaliplatin (Oxa) treatment to SH-SY5Y human neuroblastoma cells has been shown by previous studies to induce oxidative stress, which in turn modulates intracellular signaling cascades resulting in cell death. While this phenomenon of Oxa-induced neurotoxicity is known, the underlying mechanisms inv...

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Pubblicato in:PLoS One
Autori principali: Waseem, Mohammad, Sahu, Upasana, Salman, Mohd., Choudhury, Arnab, Kar, Sudeshna, Tabassum, Heena, Parvez, Suhel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521772/
https://ncbi.nlm.nih.gov/pubmed/28732061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180953
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