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ECIS technology reveals that monocytes isolated by CD14(+ve) selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα
BACKGROUND: We have previously shown that TNFα and IL-1β differentially regulate the inflammatory phenotype of human brain endothelial cells (hCMVECs). In this regard, IL-1β treatment was considerably more potent than TNFα at increasing expression of inflammatory chemokines and leukocyte adhesion mo...
में बचाया:
में प्रकाशित: | PLoS One |
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मुख्य लेखकों: | , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Public Library of Science
2017
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521748/ https://ncbi.nlm.nih.gov/pubmed/28732059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180267 |
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