Negative autoregulation of c-myc gene expression is inactivated in transformed cells.

Negative feedback regulation of c-myc gene expression has been observed in some, but not all, cell types. In order to demonstrate conclusively the existence of this mechanism and gain insight into the cause of its inactivation, we have directly examined its function in B cells and then investigated...

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Bibliographic Details
Published in:EMBO J
Main Authors: Grignani, F, Lombardi, L, Inghirami, G, Sternas, L, Cechova, K, Dalla-Favera, R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2249657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07612.x
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