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Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II molecule.

A functional analysis was undertaken of the effects of mutating single amino acid residues in the alpha chain of the I-Ak molecule (to alanine; residues 50-79) on the ability of I-Ak transfectants to process and present influenza haemagglutinin to CD4+ T cell clones specific for two major antigenic...

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Autors principals: Warren, A P, Paschedag, I, Benoist, C, Peccoud, J, Mathis, D, Thomas, D B
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC552152/
https://ncbi.nlm.nih.gov/pubmed/2123452
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