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Increased eIF-2 alpha expression in mitogen-activated primary T lymphocytes.

G0 human T cells synthesize protein at low rates and contain very low levels of eIF-2 alpha mRNA. eIF-2 alpha plays a pivotal role in the earliest regulated steps of translation initiation. We examined eIF-2 alpha gene expression in normal human T cells stimulated with PHA. Nuclear run-on assays ind...

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Detalhes bibliográficos
Main Authors: Cohen, R B, Boal, T R, Safer, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552150/
https://ncbi.nlm.nih.gov/pubmed/1701139
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