Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.

Stimulation of the T lymphocyte antigen receptor-CD3 complex (TCR-CD3) causes T cell activation by a process associated with increased phosphatidylinositol-specific phospholipase C (PI-PLC) activity. Evidence exists suggesting that GTP-binding (G) proteins, particularly the pertussis toxin (PT)-sens...

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Pubblicato in:	EMBO J
Autori principali:	Chaffin, K E, Beals, C R, Wilkie, T M, Forbush, K A, Simon, M I, Perlmutter, R M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2123451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07600.x
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