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CRISPulator: a discrete simulation tool for pooled genetic screens

BACKGROUND: The rapid adoption of CRISPR technology has enabled biomedical researchers to conduct CRISPR-based genetic screens in a pooled format. The quality of results from such screens is heavily dependent on the selection of optimal screen design parameters, which also affects cost and scalabili...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Nagy, Tamas, Kampmann, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521134/
https://ncbi.nlm.nih.gov/pubmed/28732459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1759-9
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