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In situ analysis of myelin basic protein gene expression in myelin-deficient oligodendrocytes: antisense hnRNA and readthrough transcription.

Mice homozygous for the recessive mutation myelin deficient (mld) exhibit a severe deficit in the synthesis of myelin basic protein (MBP). The primary defect in mld mice is an unusual rearrangement of the MBP gene. The mld MBP locus consists of two tandem MBP genes that span approximately 90 kb of D...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Fremeau, R T, Popko, B
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1698617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07562.x
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