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Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice

The process of follicular development involves communications between oocyte and surrounding granulosa cells. FURIN is a member of the family of proprotein convertases that is involved in the activation of a large number of zymogens and proproteins by cleavage at its recognition motif. To investigat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Meng, Tie-Gang, Hu, Meng-Wen, Ma, Xue-Shan, Huang, Lin, Liang, Qiu-Xia, Yuan, Yue, Hou, Yi, Wang, Hongmei, Schatten, Heide, Wang, Zhen-Bo, Sun, Qing-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520891/
https://ncbi.nlm.nih.gov/pubmed/28569793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.231
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