Geminin deletion in pre-meiotic DNA replication stage causes spermatogenesis defect and infertility

Geminin plays a critical role in cell cycle regulation by regulating DNA replication and serves as a transcriptional molecular switch that directs cell fate decisions. Spermatogonia lacking Geminin disappear during the initial wave of mitotic proliferation, while geminin is not required for meiotic...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: YUAN, Yue, MA, Xue-Shan, LIANG, Qiu-Xia, XU, Zhao-Yang, HUANG, Lin, MENG, Tie-Gang, LIN, Fei, SCHATTEN, Heide, WANG, Zhen-Bo, SUN, Qing-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649097/
https://ncbi.nlm.nih.gov/pubmed/28690291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2017-036
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