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Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial

Current directions in medication development for alcohol use disorder (AUD) emphasize the need to identify novel molecular targets and efficiently screen new compounds aimed at those targets. Ibudilast (IBUD) is a neuroimmune modulator that inhibits phosphodiesterase-4 and -10 and macrophage migrati...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Ray, Lara A, Bujarski, Spencer, Shoptaw, Steve, Roche, Daniel JO, Heinzerling, Keith, Miotto, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520778/
https://ncbi.nlm.nih.gov/pubmed/28091532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.10
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