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Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial

Current directions in medication development for alcohol use disorder (AUD) emphasize the need to identify novel molecular targets and efficiently screen new compounds aimed at those targets. Ibudilast (IBUD) is a neuroimmune modulator that inhibits phosphodiesterase-4 and -10 and macrophage migrati...

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Bibliografske podrobnosti
izdano v:Neuropsychopharmacology
Main Authors: Ray, Lara A, Bujarski, Spencer, Shoptaw, Steve, Roche, Daniel JO, Heinzerling, Keith, Miotto, Karen
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520778/
https://ncbi.nlm.nih.gov/pubmed/28091532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.10
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