Phosphorylated CAV1 activates autophagy through an interaction with BECN1 under oxidative stress

CAV1/Caveolin1, an integral membrane protein, is involved in caveolae function and cellular signaling pathways. Here, we report that CAV1 is a positive regulator of autophagy under oxidative stress and cerebral ischemic injury. Treatment with hydrogen peroxide enhanced autophagy flux and caused the...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Nah, Jihoon, Yoo, Seung-Min, Jung, Sunmin, Jeong, Eun Il, Park, Moonju, Kaang, Bong-Kiun, Jung, Yong-Keun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520747/
https://ncbi.nlm.nih.gov/pubmed/28542134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.71
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