A carregar...

Overexpression of Atg5 in mice activates autophagy and extends lifespan

Autophagy has been implicated in the ageing process, but whether autophagy activation extends lifespan in mammals is unknown. Here we show that ubiquitous overexpression of Atg5, a protein essential for autophagosome formation, extends median lifespan of mice by 17.2%. We demonstrate that moderate o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pyo, Jong-Ok, Yoo, Seung-Min, Ahn, Hye-Hyun, Nah, Jihoon, Hong, Se-Hoon, Kam, Tae-In, Jung, Sunmin, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753544/
https://ncbi.nlm.nih.gov/pubmed/23939249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3300
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!