Protein disulfide isomerase-mediated apoptosis and proliferation of vascular smooth muscle cells induced by mechanical stress and advanced glycosylation end products result in diabetic mouse vein graft atherosclerosis

Protein disulfide isomerase (PDI) involves cell survival and death. Whether PDI mediates mechanical stretch stress (SS) and/or advanced glycosylation end products (AGEs) -triggered simultaneous increases in proliferation and apoptosis of vascular smooth muscle cells (VSMCs) is unknown. Here, we hypo...

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Pubblicato in:Cell Death Dis
Autori principali: Ping, Suning, Liu, Shuying, Zhou, Yuhuan, Li, Ziqing, Li, Yuhuang, Liu, Kefeng, Bardeesi, Adham SA, Wang, Linli, Chen, Jingbo, Deng, Lie, Wang, Jingjing, Wang, Hong, Chen, Dadi, Zhang, Zhengyu, Sheng, Puyi, Li, Chaohong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520728/
https://ncbi.nlm.nih.gov/pubmed/28542133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.213
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