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Protein disulfide isomerase-mediated apoptosis and proliferation of vascular smooth muscle cells induced by mechanical stress and advanced glycosylation end products result in diabetic mouse vein graft atherosclerosis

Protein disulfide isomerase (PDI) involves cell survival and death. Whether PDI mediates mechanical stretch stress (SS) and/or advanced glycosylation end products (AGEs) -triggered simultaneous increases in proliferation and apoptosis of vascular smooth muscle cells (VSMCs) is unknown. Here, we hypo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ping, Suning, Liu, Shuying, Zhou, Yuhuan, Li, Ziqing, Li, Yuhuang, Liu, Kefeng, Bardeesi, Adham SA, Wang, Linli, Chen, Jingbo, Deng, Lie, Wang, Jingjing, Wang, Hong, Chen, Dadi, Zhang, Zhengyu, Sheng, Puyi, Li, Chaohong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520728/
https://ncbi.nlm.nih.gov/pubmed/28542133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.213
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